| 課程目標 |
幹細胞(stem cells)是一群尚未完全分化的細胞，同時具有分裂增殖成另一個與本身完全相同的細胞，以及分化成為多種特定功能的體細胞兩種特性。人類多功能性的胚胎幹細胞已可在體外培養與繁殖，且在體外能夠分化成為二百多種器官與組織的細胞，其在器官與組織的移植、新藥開發、基因療法、治療癌症等方面具有無限的發展潛力。組織工程是整合細胞學、生醫材料、生化學、基因體學等多項科學應用，由細胞層次進行醫療，製備具有功能之組織或器官，以修復、替換、再生因疾病、創傷或老化而損壞的組織或器官。組織工程的應用範圍除了涵蓋組織及器官替換，還延伸到細胞治療與藥物傳輸等領域。本課程目的在於教授了解此兩個領域的基礎科學並介紹幹細胞及組織工程在各種組織器官之再生及多種疾病的應用。 |
Objectives |
Stem cells are a group of undifferentiated cells that has ability to proliferate indefinitely and, when specifically stimulated, differentiated to various types of somatic cells. Multipotent embryonic stem cells are now being cultured in vitro successfully, and could be differentiate to more than 200 different types of cells in various organs and tissues. These types of cells can be used in organ transplantation, drug development, gene therapy, and cancer therapy. Tissue engineering is an interdisciplinary subject that integrating the fields of cell biology, biomedical material, biochemistry, genomic. The research aims at preparation of functional organ or tissue that would replace or repair diseased ones. The purpose of this course is to teach basic science for the understanding of these two principles, and to introduce their application in the repair and regeneration of various tissue and organs. |