當期課號 | 7245 | Course Number | 7245 |
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授課教師 | 陳永福 | Instructor | CHEN,YUNG FU |
中文課名 | 計算生物學 | Course Name | Computational Biology |
開課單位 | 資訊管理系碩士班二A | Department | |
修習別 | 選修 | Required/Elective | Elective |
學分數 | 3 | Credits | 3 |
課程目標 | 人類基因組是由大約三十億鹼基對(A, T, C, G)所組成。將這些資料的順序正確排列就是基因定序。而這只是一個開端而已,隨之而來的是更大量的分析資料,在這大量的資料裡,有用的資料卻是隱藏在許多雜訊之中,計算生物學領域就是要找出有用的資訊,其主要的重點是有關如何儲存、管理、傳輸、進而分析生物相關的大量資訊。 | Objectives | 1.Sequence Alignment 2.Evolutionary Trees 3.Superstrings 4.Protein Structure 5.System Biology 6.String Matching 7.Superstructures 8.RNA Structures 9.Genome Rearrangement 10.Pattern Discovery 11.Divide-and-Conquer 12.Sorting by Reversal 13.Visual Display |
教材 | Bioinformatics and Functional Genomics by J. Pevsner, Wiley-Liss 2003 | Teaching Materials | Bioinformatics and Functional Genomics by J. Pevsner, Wiley-Liss 2003 |
成績評量方式 | 1. 出席:10% 2. 作業:30% 3. 期中考試:30% 4. 期末報告:30% |
Grading | 1.Attendance:10% 2.Homework: 30% 3.Mid-Term Exam:30% 4.Final Exam:30% |
教師網頁 | www.csie.dyu.edu.tw/~yfbchen/ | ||
教學內容 | Chap 0: Cell Function, Protein and DNA (細胞功能、蛋白質、DNA)、Transcription and Translation (基因之轉錄及轉譯) Chap 1: Introduction to Bioinformatics(生物資訊學簡介) Chap 2: Access to Sequence Data and Literature Information(基因序列資料和文獻資訊存取) Chap 3: Pairwise Sequence Alignment (雙序列比對) Chap 4: Basic Local Alignment Search Tool (BLAST序列比對工具 ) Chap 5: Basic Local Alignment Search Tool (BLAST序列比對工具 ) Chap 6: Bioinformatic Approaches to Gene Expression(利用生物資訊探討基因表現) Chap 7: Gene Expression: Microarray Data Analysis(基因表現:微晶片陣列資料分析) Chap 8: Protein Analysis and Proteomics(蛋白質分析及蛋白質體學) Chap 9: Protein Structure(蛋白質結構) Chap 10: Multiple Sequence Alignment(多序列比對) Chap 11: Molecular Phylogeny and Evolution(分子種系和演化) Chap 12: Completed Genomes and the Tree of Life(已完成之生物基因體和生命樹) |
Syllabus | Chap 0: Cell Function, Protein and DNA, Transcription and Translation Chap 1: Introduction to Bioinformatics Chap 2: Access to Sequence Data and Literature Information Chap 3: Pairwise Sequence Alignment Chap 4: Basic Local Alignment Search Tool Chap 5: Basic Local Alignment Search Tool Chap 6: Bioinformatic Approaches to Gene Expression Chap 7: Gene Expression: Microarray Data Analysis Chap 8: Protein Analysis and Proteomics Chap 9: Protein Structure Chap 10: Multiple Sequence Alignment Chap 11: Molecular Phylogeny and Evolution Chap 12: Completed Genomes and the Tree of Life |